王翠竹

作者: 时间:2021-10-14 点击数:

姓名

王翠竹

职称

副教授

办公地点

基础医学院125室

办公电话

0431-85619803

邮箱

wangcuizhu@jlu.edu.cn

教育背景

2013-2018,博士,药物化学,伟德bv1946官网

2009-2013,学士,药学,伟德bv1946官网

工作经历

2022-至今,副教授,伟德bv1946官网,BV伟德国际1946

2021-2022,讲师,伟德bv1946官网,BV伟德国际1946

2019-2021,博士后,基础医学院,BV伟德国际1946

主讲课程

药剂学

研究领域

天然药物;化学成分及生物活性研究;创新药物开发

科研成果

一、SCI文章

1. Huangfu H M, Du S L, Zhang H, Wang H C; Zhang Y, Yang Z, Zhang X W, Ren S C, Chen S Y, Wang C Z*, Zhang Y D*, Zhou Y M*. Facile engineering of resveratrol nanoparticles loaded with 20(S)-protopanaxadiol for the treatment of periodontitis by regulating the macrophage phenotype, Nanoscale, 2023, 15 (17): 7894-7908.

2. Wang C Z, Tan L Y, Liu J T, Fu D X, Wang C X, Li P Y, Li Z, Liu J P. Integrated Metabolomics and Network Pharmacology to Decipher the Latent Mechanisms of Protopanaxatriol against Acetic Acid-Induced Gastric Ulcer, International Journal of Molecular Sciences, 2022, 23(20): 12097.

3. Wang C Z, Dong Q H, Wu F L, Li Z, Li P Y, Liu J P, Wang F*. A new alkynol compound from Platycodins folium and its cytotoxicity, Natural Product Research, 2021, 35 (20) : 3487-3493.

4. Wang C Z, Yuan Y Z, Pan H, Alan Chen-Yu Hsu, Chen J L, Liu J P, Li P Y, Wang F. Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics, International Journal of Molecular Sciences, 2020, 21(7): 2577.

5. Wang C Z, Lin H Q,Yang N, Wang H, Zhao Y, Li P Y, Liu J P, Wang F. Effects of Platycodins Folium on Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics, Molecules, 2019, 24(9), 1712.

6. Wang C Z, Zhang N Q, Wang Z Z, Qi Z, Zhu H L, Zheng B Z, Li P Y, Liu J P. Nontargeted Metabolomic Analysis of Four Different Parts of Platycodon grandiflorum Grown in Northeast China, Molecules, 2017, 22(8): 1280.

7. Wang C Z, Zhang N Q, Wang Z Z, Qi Z, Zheng B Z, Li P Y, Liu J P. Rapid characterization of chemical constituents of Platycodon grandiflorum and its adulterant Adenophora stricta by UPLC-QTOF-MS/MS, Journal of Mass Spectrometry, 2017, 52(10): 643-656.

8. Jin L F, Wang C Z, Liu J P, Li P Y, Li J, Cui X L, Wang Y. Pseudo-ginsengenin DQ ameliorated aconitineinduced arrhythmias by influencing Ca2+ and K+ currents in ventricular myocytes, RSC Advances, 2020, 10, 25999.

9. Zhang N Q, Wang C Z, Wang Z Z, Li Z, Sai J Y, Meng Y, Wang F, Li P Y, Liu J P. Anti-myocardial ischaemic effect of pseudoginsenoside F11 by inhibiting expression of beta1-adrenoceptor in rats with coronary artery ligation, Journal of Functional Foods, 2017, 36:224-232.

10. Zhang K, Liu Y, Wang C Z, Li J N, Xiong L X, Wang Z Z, Liu J P, Li P Y. Evaluation of the gastroprotective effects of 20(S)-ginsenoside Rg3 on gastric ulcer models in mice, Journal of Ginseng Research, 2019, 43 (4): 550-561.

二、授权专利

1. 王翠竹, 王振洲, 林红强, 周柏松, 祁增, 王亚茹, 杨娜, 李雅萌, 朱海林, 赵天一, 刘金平, 李平亚. 桔梗新醇及其提取方法及其医药用途, 2021-04-16, 中国, ZL 2018 1 0365192.4.

2. 刘金平, 王彩霞, 王放, 王翠竹, 林红强, 吴浚哲, 李卓俏, 刘瀚璘, 吕浩铭.齐墩果酸-28-O-β-D-吡喃葡萄糖苷在制备抗结肠炎药物中的应用, 2024-3-15, 中国, ZL 2023 1 1695482.2

3. 王放, 张晶, 刘金平, 王翠竹, 郑敬彤, 刘俊丽, 张晋榕, 王国强, 关雪娃, 董兵. (20S, 24R)-ocotillol型人参皂苷甘氨酸衍生物、其制备方法及用途, 2022-02-08, 中国, ZL 2019 1 1112761.5.

4. 祁增, 李平亚, 王振洲, 周柏松, 王翠竹, 王涵, 吴福林, 董庆海, 林红强, 刘金平. 拟人参皂苷12-酮-PF11及提取方法及其医药用途, 2021-02-12, 中国, ZL 2018 1 0365085.1.

5. 祁增, 李平亚, 王振洲, 王放, 关雪娃, 王翠竹, 周柏松, 刘金平, 王亚茹, 林红强. 达玛烷型皂苷元S及其提取方法及其医药用途, 2021-02-02, 中国, ZL 2018 1 0313545.6.

三、参编著作

1. 李平亚, 林美妤, 刘金平.《人参皂苷NMR标准图谱(2013-2023)》, 北京工业出版社, 2024.

2. Yu Bin, Li Ning, Fu Caiyun.《Privileged Scaffolds in Drug Discovery》, ELSEVIER出版社, 2023.

3. 李平亚, 刘金平, 李卓.《西洋参营养成分及功能因子》, 化学工业出版社, 2021.

4. Li Pingya, Liu Jinping.《Ginseng Nutritional Components and Functional Factors》, Chemical Industtry Press Co.td, Springer, 2020.

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