代表性文章/Representative Publications: 1. Xinying Wang , Linlin Lv , Tongyan Liu , Fengrui Yang , Xuan Han , Qingxiang Guan*. Catechol chitosan coated dual-loaded liposomes based on oxidation and sacchariffcation mechanisms for enhancing skin anti-aging effects. International Journal of Biological Macromolecules, 2024, 256: 128342 2. Shangmin Yu, , Xinying Wang,, Linlin Lv, Tongyan Liu, Qingxiang Guan*. Borneol-modiffed PEGylated graphene oxide as a nanocarrier for brain- targeted delivery of ginsenoside Rg1 against depression. International Journal of Pharmaceutics, 2023, 643: 123284 3.Wang, Xinying, Liu, Yura,Liu, Tongyan,Mustafa, Fara, Qingxiang Guan*. Doxorubicin and Zinc phthalocyanine loaded pH-responsive FA-BSP-SA/TPGS micelles for synergistic chemo-photodynamic therapy against tumors. Journal of Drug Delivery Science and Technology, 2022, 76: 103703. 4.Yu Shangmin, Liu Shan, Wang Ning,Yu Di,Qin Meng,Wu Ji, Guan Qingxiang*. Novel insights into antidepressant mechanism of Kai Xin San formula: Inhibiting NLRP3 inflammasome activation by promoting autophagy.Phytomedicine,93:153792 5.Yuran Liu, Cheng Sun, Guangyuan Zhang, Ji Wu, Long Huang, Jin Qiao, Qingxiang Guan*. Bio-responsive Bletilla striata polysaccharide-based micelles for enhancing intracellular docetaxel delivery. International Journal of Biological Macromolecules, 2020, 142: 277–287. 6. Zhang Guangyuan, Qiao Jin,Liu Xin, Liu Yuran, Wu Ji, Huang Long, Ji Danyang, Guan Qingxiang*. Interactions of self-assembled Bletilla Striata polysaccharide nanoparticles with bovine serum albumin and biodistribution of its docetaxel-loaded nanoparticles. Pharmaceutics, 2019, 11(1): 43. 7. Qiao Jin, Ji Danyang, Sun Shili, Zhang Guangyuan, Liu Xi, Sun Bingxue, Guan Qingxiang*. Oral bioavailability and lymphatic transport of pueraria flavone-loaded self-emulsifying drug delivery systems containing sodium taurocholate in rats. Pharmaceutics, 2018, 10(3):147. 8. Sun Dandan, Wang Miao, Ji Danyang, Qiao Jin, He, Tong, Liu, Xin, Guan, Qingxiang*. Synthesis of a reduction-sensitive Bletilla striata polysaccharide amphiphilic copolymer, Chinese Chemical letters, 2018, 29(6):831-833. 9. Zhao Lichun, Sun Dandan, Lu Haibin, Han Bing, Zhang Guangyuan, Guan Qingxiang*. In vitro characterization of pH-sensitive Bletilla Striata polysaccharide copolymer micelles and enhanced tumour suppression in vivo. Journal of pharmacy and pharamcology. 2018,70(6): 797-807. 10. Hang Gao, Miao Wang, Dandan Sun, Shilin Sun, Cheng Sun, Jianguo Liu, Guan Qingxiang*. Evaluation of the cytotoxicity and intestinal absorption of a self-emulsifying drug delivery system containing sodium taurocholate. European Journal of Pharmaceutical Sciences 2017,106:212-219. 书籍著作/Books: 1. 现代实用中药新剂型新技术,编委,北京:人民卫生出版社,2007. 2. 国家执业药团队格考试考题纵览与全真模拟系列丛书- 药学专业知识(二). 主编. 北京:军事医学科学出版社,2008. 3. 国家执业药团队格考试考题纵览与全真模拟系列丛书- 药学专业知识(二).主编. 北京:军事医学科学出版社,2009. 4. 中药现代研究与开发,编委,北京:中国科学出版社,2010. 5. 医师案头用药参考,副主编,北京:中国中医药出版社,2015. 1. New dosage Forms and novel Technologies of Modern Practical Traditional Chinese Medicine, Editorial Board Member, Beijing: People's Health Publishing House, 2007 2. Overview of National Practicing Pharmacist Qualification Exam for Examination Questions and Comprehensive Simulation Series - Pharmaceutical Professional Knowledge (II) Editor in Chief, Beijing: Military Medical Science Press, 2008 3. Overview of National Practicing Pharmacist Qualification Exam for Examination Questions and Comprehensive Simulation Series - Pharmaceutical Professional Knowledge (II). Editor in Chief, Beijing: Military Medical Science Press, 2009 4. Modern Research and Drug Development of Traditional Chinese Medicine, Editorial Board Member, Beijing: China Science Press, 2010 5. Physician's Medication Reference, Associate Editor in Chief, Beijing: China Traditional Chinese Medicine Press, 2015 发明专利/Patents for invention: 1.管清香,林天慕,鲁晶雯,陈倩. 叶黄素眼用纳米囊原位凝胶制剂及其制备方法[P]. 中国:ZL 2011 1 0144619.6 2. 管清香, 吕琳琳. 一种白芨多糖铁复合物及其制备方法与应用. [P]. 中国:ZL 2023 1 0538615.9 1. Guan Qingxiang, Lin Tianmu, Lu Jingwen, Chen Qian. Fabrication method and formulation of Lutein ophthalmic nanocapsule in situ gel [P] China: ZL 2011 1 0144619.6 2. Guan Qingxiang, Lv Linlin. A iron complex based on Bai Ji polysaccharide and its preparation method as well as its application [P] China: ZL 2023 1 0538615.9 科研成果获奖/Research Awards: 1. “制剂新技术的研究及其在创新药物开发中的应用”获吉林省科技进步二等奖(第1名),2015. 2. “治疗咽炎药物的研究”获中华医学科技三等奖(第3名),2010. 3. “可生物降解固体脂质纳米粒的制备、表征及药物的体外释放”获吉林省自然科学学术成果三等奖(第1名),2012. 1." The research on new formulation technologies and their applications in innovative drug development " won the second prize (first place) of Jilin Province Science and Technology Progress Award, 2015 2. "The research of drugs for treating pharyngitis" won the third prize (third place) in Chinese Medical Science and Technology, 2010 3. "Preparation, characterization and in vitro drug release of a biodegradable solid lipid nanoparticles" won the third prize (first place) of Jilin Province Natural Science Academic Achievement Award, 2012 上一篇:郝秀华 |