科研成果 |
近五年主持的科研项目： 1.国家自然科学基金委员会,青年科学基金项目, 82003752, SIRT1去乙酰化修饰HMGB1减轻心肌缺血再灌注损伤的机制研究及人参皂苷Rg2的干预作用, 2021-01-01至2023-12-31, 24万元,在研 2.吉林省科技发展计划,优秀青年人才基金项目, 20190103084JH,基于SIRT1信号通路的人参皂苷Rg2心 脏保护作用的机制研究, 2019-01至2020-12, 7.0万元,结题代表性论文：1.Yan Xue; Xiaofeng Yu; Xiuhang Zhang; Ping Yu; Yuangeng Li; Wenwen Fu; Jiaao Yu; Dayun Sui; Protective effects of ginsenoside Rc against acute cold exposure-inducedmyocardial injury in rats, Journal of Food Science, 2021, 86(7): 3252-3264. 2.Yan Xue; Wenwen Fu; Yanzhe Liu; Ping Yu; Mingyang Sun; Xin Li; Xiaofeng Yu; Dayun Sui ; Ginsenoside Rb2 alleviates myocardial ischemia/reperfusion injury in rats through SIRT1 activation, Journal of Food Science, 2020, 85(11): 4039-4049. 3.Yi Wu; Heming Cui; Yuying Zhang; Ping Yu; Yuangeng Li; Dan Wu; Yan Xue; Wenwen Fu ; Inonotus obliquus extract alleviates myocardial ischemia/reperfusion injury by suppressing endoplasmic reticulum stress, Molecular Medicine Reports, 2021, 23(1): 77. 4.Wenwen Fu; Huali Xu; Xiaofeng Yu; Chen Lyu; Yuan Tian; Minyu Guo; Jiao Sun; Dayun Sui ; 20(S)-Ginsenoside Rg2 attenuates myocardial ischemia/reperfusion injury by reducing oxidative stress and inflammation: role of SIRT1, RSC Advances, 2018, 8(42): 23947-23962. 5.Wenwen Fu; Xiaofeng Yu; Zeyuan Lu; Fanfan Sun; Yuchen Wang; Ying Zhang; Yue Zhang; Yanping Chen; Huali Xu; Dayun Sui ; Protective effects of ginsenoside Rb2 on myocardial ischemia in vivo and in vitro, International Journal of Clinical and Experimental Medicine, 2016, 9(6): 9843-9855.获奖情况：大鼠非呼吸机下急性心肌梗死系列心血管疾病模型的建立与应用，吉林省科技进步二等奖，2019（第四完成人 ） |
