科研成果 |
Publications：1.Yuanhua Lu, Jie Ma*, Jian Lin, Yafei Tian, Yongjun Ma, Wei Wang, Jialin Li, Hugang Zhang, Ping Jiao*.Cell membrane breakage and triggering T cell infiltration are involved in human telomerase reverse transcriptase (hTERT) promoter-driven novel peptide KK-64 for liver cancer gene therapy. Bioengineered. Published online Dec 14 2021. 2.L.X Chen, J. Qian, Z. Wang, X.L. Cong and J.Ma*. Integrated proteomics and transcriptomics identified novel potential prognostic biomarkers in ovarian cancer. J Biol Regul Homeost Agents. Nov-Dec 2021;35(6). Doi: 10.23812/21-322-A. Ahead of Print. 3.Lixin Chen, Ji Qian, Qinghua You*, Jie Ma*. LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway. Bioengineered. 2021;12(2):10089-100. Jian Lin, Yuanhua Lu, Bizhou Wang, Ping Jiao* and Jie Ma* Analysis of immune cell components and immune-related gene expression profiles in peripheral blood of patients with type 1 diabetes mellitus. J Transl Med (2021) 19:319. 4.Tongjian Zhao, Jie Ma, Lulu Li, Wenjing Teng, Yafei Tian, Yongjun Ma, Wei Wang, Weiqun Yan*, Ping Jiao*. MKP-5 Relieves Lipotoxicity-Induced Isletβ-Cell Dysfunction and Apoptosis via Regulation of Autophagy. Int J Mol Sci. 2020 Sep 28;21(19):E7161. doi: 10.3390/ijms21197161. 5.Xue-Kun Liu, Yan-Qiu Wang, Tong-Jian Zhao, Yuan-Hua Lu, Jia-Nan Zhao, Xiao-Yu Geng, Jie Ma* Design and Synthesis of 7-Azaindole Derivatives and Their Antitumor and Analgesic Activities. J.Chem.Soc.Pak., 42(03), 2020, 460-468. 6.Chao Zhou, Jie Ma*, Yuanhua Lu, Wan Zhao, Bingxue Xu, Jian Lin, Wenjun Ma, Yafei Tian, Qi Zhang, Wei Wang, Weiqun Yan, Ping Jiao*. TERT promoter regulating melittin expression induces apoptosis and G0/G1 cell cycle arrest in esophageal carcinoma cells. Oncology Letters, ,2021,21:16. 7.Yuanhua Lu, Jie Ma*, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Chao Zhou, Xiu Liu, Wenjing Teng, Wei Wang,Weiqun Yan, Ping Jiao*. The role of MKP-5 in adipocyte-macrophage interactions during obesity. Obesity Facts, 2020（13）：1，86-101. 8. Song Z, Ma J, Lu Y, Zhou C, Zhao T, Ai X, Wei X, Lin J, Wang W, Yan W, Jiao P. The protective role of the MKP-5-JNK/P38 pathway in glucolipotoxicity-induced isletβ-cell dysfunction and apoptosis. Exp Cell Res. 2019(382):1,111467. 2019 Sep 1. pii: S0014-4827(19)30307-6. doi: 10.1016/j.yexcr.2019.06.012. 9. Zhan JY, Ma J*, Zheng QC*. Molecular dynamics investigation on the Asciminib resistance mechanism of I502L and V468F mutations in BCR-ABL. J Mol Graph Model. 2019 Jun;89:242-249. 10.Yuze Yuan, Nan Ran, Lingxin Xiong, Guoqiang Wang, Xuewa Guan, Ziyan Wang, Yingqiao Guo, Zhiqiang Pang, Keyong Fang, Junying Lu, Chao Zhang, Ruipeng Zheng, Jingtong Zheng, Jie Ma*, Fang Wang*. Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies. J Immunol Res. 2018; 2018: 1943497. Published online 2018 Jun 28. 11. Chao Zhou, Jie Ma, Mengyuan Su, Dan Shao, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Yan Meng, Ping Jiao. Down-regulation of STAT3 induces the apoptosis and G1 cell cycle arrest in esophageal carcinoma ECA109 cells. Cancer Cell Int. 2018; 18: 53. 12. Shao D, Ma J, Zhou C, Zhao JN, Li LL, Zhao TJ, Ai XL, Jiao P. STAT3 down-regulation induces mitochondria-dependent G2/M cell cycle arrest and apoptosis in esophageal carcinoma cells. Clin Exp Pharmacol Physiol. 2017, 44(3):413-420. 13. Li X, Shen J, Tan L, Zhang Z, Gao D, Luo J, Cheng H, Zhou X, Ma J, Ding K, Lu X. Design and synthesis of N-(4-aminopyridin-2-yl)amides as B-Raf(V600E) inhibitors. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2760-2763. 14. Jiang S, Wang Y, Ren D, Li J, Yuan G, An L, Du P, Ma J*.Antidiabetic mechanism of Coptis chinensis polysaccharide through its antioxidant property involving the JNK pathway. Pharm Biol. 2015 Jul;53(7):1022-1029. 15. Dejun Sun,*, Miaonan Sun, Wenhe Zhu,, Zhiding Wang, Yuefei Li, Jie Ma,*The Anti-Cancer Potency and Mechanism of a Novel Tumor-Activated Fused Toxin, DLM. Toxins 2015, 7(2), 423-438. 16. Rieder F, Nonevski I, Ma J, Ouyang Z, West G, Protheroe C, Depetris G, Schirbel A, Lapinski J, Goldblum J, Bonfield T, Lopez R, Harnett K, Lee J, Hirano I, Falk G, Biancani P, Fiocchi C.T-Helper 2 Cytokines, Transforming Growth Factorβ1, and Eosinophil Products Induce Fibrogenesis and Alter Muscle Motility in Patients With Eosinophilic Esophagitis. Gastroenterology. 2014 May;146(5):1266-1277. 17. Haotian Wang, Xinmin Zhang, Ning Kong, Anhui Wei, Yanhong Zhang, Jie Ma*. Expression, purification and characterization of a recombinant Tat47-57-Oct4 fusion protein in Pichia pastoris. Molecular Medicine Reports. 2014, 92(2): 471-475.Patents for Patents for inventions：1． Preparation of TAT-EGF fusion protein and its application in beauty mask.(ZL 201711470311.4) 2． A new antitumor polypeptide and its applications.（ZL 201910609086.0） 3． The construction of a tumor targeted plasmid pcTERT and its application.（ZL 201810543497.X） |
